Best Peptide Protocols
    Sexual HealthSingle

    Melanotan I 10mg: Dosage, Reconstitution & Research Protocol Guide

    Dosing ranges, reconstitution steps, administration details, cycle length, and storage guidance for Melanotan I (10 mg Vial).

    Strength & Form:10 mg Vial
    Melanotan I (10 mg Vial) peptide vial

    Melanotan I (10 mg Vial)

    10 mg Research Peptide

    Quick Facts

    Type
    Single
    Category
    Sexual Health
    Vial Strength
    10 mg
    Status
    Research

    Research Purposes Only

    This information is provided for educational purposes only. This content is not intended to diagnose, treat, cure, or prevent any disease. Always consult with qualified healthcare professionals.

    Download Guide

    Save the complete Melanotan I 10mg research guide as a PDF.

    Educational and research use only. Not medical advice.

    Reference

    Sources used for this guide are listed in our research database .

    What Is Melanotan I 10mg?

    Melanotan I 10mg Vial Overview

    Melanotan I (Afamelanotide) is a linear 13-amino acid synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH) that activates melanocortin-1 receptors (MC1R). It stimulates melanogenesis independent of UV exposure. Unlike Melanotan II, it has minimal effects on sexual function or appetite.

    Melanotan I 10mg Quick Reference

    Melanotan I 10mg Vial Specifications

    Peptide
    Melanotan I (10 mg Vial) (NNMT inhibitor)
    Vial Content
    10 mg total peptide
    Category
    Sexual Health
    Administration Method
    Subcutaneous injection
    Common Use Case
    UV-independent skin tanning and photoprotection

    Melanotan I 10mg Compared With Other Formats

    Details that distinguish this 10 mg format include:

    • Selective MC1R activation (tanning without sexual side effects)
    • EU-approved (Scenesse®) for EPP
    • Photoprotective against UV-induced DNA damage

    How Does Melanotan I Work?

    Melanotan I Mechanism of Action

    Melanotan I (Afamelanotide) is a linear 13-amino acid α-MSH analog that selectively activates MC1R on melanocytes. This stimulates eumelanin production, providing a darker skin pigment that absorbs UV radiation. Unlike Melanotan II, its MC1R selectivity avoids significant effects on sexual function, appetite, or other melanocortin-mediated pathways.

    What Are the Potential Benefits of Melanotan I?

    Melanotan I Research Findings and Observed Outcomes

    Findings and reported areas of study for Melanotan I (10 mg Vial) include:

    • Selective melanogenesis without systemic effects
    • UV-independent tanning
    • Photoprotection against DNA damage
    • Approved therapeutic for EPP

    These observations are discussed for research and educational reference only and are not medical claims.

    What Do You Need to Reconstitute Melanotan I 10mg?

    Melanotan I 10mg Supplies for Reconstitution and Handling

    • •Insulin syringes (29–31 gauge)
    • •Bacteriostatic water
    • •Alcohol prep pads
    • •Sharps container

    Supplies listed are for laboratory handling and research preparation purposes only.

    Melanotan I 10mg Administration and Research Protocol

    Melanotan I Injection Route, Frequency and Timing

    RouteSubcutaneous injection
    FrequencyEvery other day during loading, then maintenance
    TimingAny time of day

    Melanotan I 10mg Dosage Guide

    Melanotan I Dosage Ranges

    The ranges below pair the listed dose with the draw volume for this product strength.

    Low Range0.5 mg per dose
    Standard Range1 mg per dose
    Upper Range1.5 mg per dose

    Melanotan I 10mg Dosage to Syringe Units

    Based on reconstitution below

    Target Daily DoseDraw VolumeUnits
    0.5 mg0.10 mL10 units
    1 mg0.20 mL20 units
    1.5 mg0.30 mL30 units

    This dosing table is unique to the 10 mg vial. Units refer to markings on a standard U-100 insulin syringe (1 unit = 0.01 mL).

    How Long Does a Melanotan I 10mg Vial Last?

    Melanotan I 10mg Duration by Research Dose

    At common research doses, one 10 mg vial of Melanotan I typically supports:

    0.5 mg per dose~20 doses
    1 mg per dose~10 doses
    1.5 mg per dose~7 doses

    Loading over 2–3 weeks, maintenance 1–2 times/week.

    How to Reconstitute Melanotan I 10mg

    Melanotan I 10mg Reconstitution With Bacteriostatic Water

    This section applies specifically to the Melanotan I (10 mg Vial).

    Recommended Diluent
    Bacteriostatic water
    Diluent Volume
    2 mL
    Final Concentration
    5 mg/mL

    Melanotan I 10mg Mixing Instructions

    1. 1Remove the vial from storage and allow it to reach room temperature (10–15 minutes).
    2. 2Wash hands thoroughly and prepare a clean workspace with all supplies.
    3. 3Using a sterile syringe, draw the appropriate volume of bacteriostatic water.
    4. 4Clean the rubber stopper of the vial with an alcohol prep pad.
    5. 5Insert the needle at a slight angle and slowly inject the diluent down the inner wall of the vial.
    6. 6Gently swirl or roll the vial until fully dissolved; the solution should appear clear and colorless.
    7. 7Label the vial with reconstitution date and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light. Use within 2–4 weeks.

    Melanotan I Stacks and Research Combinations

    Melanotan I and Compatible Research Pairings

    In research settings, Melanotan I (10 mg Vial) is sometimes paired with peptides such as:

      Typically used standalone.

      Factors That May Affect Melanotan I Research Outcomes

      Supporting Factors for Melanotan I Research

      Factors recorded alongside this protocol include:

      • Controlled UV exposure for optimal results
      • Sunscreen to prevent overexposure
      • Monitor skin changes
      • Adequate hydration

      These factors can affect how research observations are interpreted.

      Melanotan I Side Effects and Safety Considerations

      Melanotan I 10mg Tolerability Notes

      Better tolerated than Melanotan II due to MC1R selectivity.

      Some individuals report:

      • Nausea (milder than MT-II)
      • Facial flushing
      • Injection site reactions
      • Mole darkening

      How to Store Melanotan I Before and After Reconstitution

      Melanotan I 10mg Storage Requirements

      Unreconstituted
      Refrigerate or freeze
      Reconstituted
      Refrigerate at 2–8°C
      Post-Mix Stability
      Up to 4 weeks

      Who Should Avoid Melanotan I?

      This peptide is generally not recommended for:

      • Pregnant or breastfeeding individuals
      • History of melanoma or skin cancer
      • Those with many atypical moles
      • Anyone advised otherwise by a healthcare professional

      Melanotan I 10mg FAQs

      Is Melanotan I safer than Melanotan II?

      Melanotan I is more selective (MC1R only) and has EU regulatory approval for EPP. It avoids the sexual and appetite side effects of Melanotan II.

      Where to Buy Melanotan I 10mg for Research

      Melanotan I 10mg Purchasing and Research Supply Notes

      Before ordering Melanotan I (10 mg Vial), review the product label, available testing documents, and storage instructions.

      Check the ResearchLabs listing for:

      • Available testing documents
      • Product strength and concentration
      • Storage and handling instructions
      • Current product availability

      Confirm the product strength and storage requirements before ordering. Products are for laboratory research only and are not for human consumption.

      Related Sexual Health Peptides